Fall 2024: 28 October – 1 November 2024
Instructor Information
Shelley Facente, PhD, MPH
Principal/owner of Facente Consulting
Adjunct Professor, University of California, Berkeley
sfacente@berkeley.edu
Pre-Readings
Facente SN, Grebe E, Maher AD, Fox D, Scheer S, Mahy M, Dalal S, Lowrance D, Marsh K. Use of HIV Recency Assays for HIV Incidence Estimation and Other Surveillance Use Cases: Systematic Review. JMIR Public Health Surveill. 2022 Mar 11;8(3):e34410. doi: 10.2196/34410. PMID: 35275085; PMCID: PMC8956992. https://pubmed.ncbi.nlm.nih.gov/35275085/
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 2021;372:n71. doi: 10.1136/bmj.n71
Course Outline and Resources
Outline | Activity links and worksheets |
Day one: Monday, 28 Oct Slides -What is a systematic review (SR)? -Why and how are SRs used? -What is a meta-analysis (MA)? -Overview of PROSPERO registration and PRISMA guidelines -Defining the review question (PICOs) -Inclusion and exclusion criteria -Practice defining the research question in small groups | PRISMA Checklist Activity **PRISMA Checklist **PRISMA Abstract Checklist Facente (2022) JMIR Public Health Surveillance Criteria Practice **Criteria Worksheet Marsh (2023) Journal of Pediatric Surgery Zulfigar (2023) PLOS One Cieslik (2020) Complementary Therapies in Medicine Yu (2022) Asian Journal of Surgery Defining the Research Question Practice **PICOS Worksheet Mobile Men Study |
Day two: Tuesday, 29 Oct Slides (updated with full Zotero demo) -Searching for records/studies (PubMed, Embase, PsychINFO, other) -Practice searching for records/studies in small groups -Screening records/studies -Extracting and organizing data -Developing Figure 1 | Searching for Records Practice MeSH Term Search (MeSH on Demand) PubMed Screening Studies Practice Screening Worksheet Diagram **Screening Studies Worksheet Extracting Data Extracting Data Quick Sheet |
Day three: Wednesday, 30 Oct Slides -Continued practice searching, screening, and extracting data -Summarizing data & meta-analysis | Zotero Demo Zotero Plug-In to Bulk Remove Duplicates Sample Screening and Data Extraction Tools Appalachian SRMA Screening Tool Appalachian SRMA Data Extraction Tool Appalachian SRMA (Publication) |
Day four: Thursday, 31 Oct Slides -Evaluating risk of bias (study quality) -Evaluating publication bias -Sensitivity analyses and stratified analyses -Understanding SRMA limitations -Interpreting and reporting results | Sample Risk of Bias Evaluation Tool Appalachian SRMA ROB Evaluation Tool Practice in Excel Simple funnel plot EXAMPLES **Simple funnel plot TEMPLATE Wartolowska (2014) BMJ Lorenzetti (2023) Journal of the International AIDS Society |
Day five: Friday, 1 Nov Slides -Review of special types of SRs and MAs -Review of the key takeaways from the week -Continued practice and opportunity for questions |
Resources:
General SRMA guidelines and information
- Cochrane Handbook: The premier handbook on how to complete SRMA
- PROSPERO: SR prospective registration
- PRISMA Statement: Published guidelines for conducting SRMAs, includes checklists to guide work
- PICO Information: Guidance for defining your review question
- RoB 2 Guidance: Guidance for using the RoB 2 Template
Templates and tools
- Zotero: A free software for managing your references
- PRISMA Checklist: The PRISMA checklist to guide your work
- PRISMA Flow Diagram Generator: Tool for creating the PRISMA flow diagram
- Screening Tool Template: Template for developing screening tools
- RoB 2 Template: Template for risk of bias assessment
- RobVis tool: Tool for creating the risk of bias assessment plots
- Excel workbook to create a funnel plot: Template for creating a funnel plot in Excel
- Simple funnel plot template: Template for creating a funnel plot in Excel
Common Systematic Review software
- RevMan (Review Manager, by Cochrane)
- EPPI-Reviewer (developed by the Evidence for Policy & Practice Information & Coordinating Centre)
Tutorials and tips
- MA tutorial slides: Step by step tutorial to complete a meta-analysis
- How to, Forest Plot in Excel: Tutorial on how to create a forest plot in Excel
- PubMed Search Tips: Tips on how to best search on PubMed
- How to combine search sets (video): A video tutorial on how to combine search sets
- Best practices for screening studies: Tips on screening studies
Databases